Abstract: Nineteen genes up-regulated by Ectropic obliqua attack from tea plants were isolated by suppression subtractive hybridization（SSH），differential screening，and real-time RT-PCR analysis. These genes were involved in JA synthesis，cell wall modification，secondary metabolism，carbohydrate metabolism，pathogen defensive response and oxidative stress protection. Among these genes，15 clones were firstly isolated from tea plants，and 4 clones firstly found in the studies of molecular mechanism of plant-insect interactions，up to day. The results showed that Ectropic obliqua attack up-regulated defense related genes and induced tea defense responses.

Key words: tea plant, Ectropic obliqua, insect feeding, gene expression