Abstract: In this experiment，‘Hongyan’strawberry fruits were used as the experimental materials to explore the biocontrol efficacy and mechanism of inducing strawberry resistance by inoculation with Hanseniaspora uvarum，Botrytis cinerea，H. uvarum challenged with B. cinerea. The results showed that H. uvarum can compete for nutrition and space in the wound by large reproduction，having good biocontrol effect on the gary mold of strawberry，and the lesion diameter of strawberry decreased significantly in H. uvarum treatment. Results of gene expression abundance indicated that the WRKY1，NPR1，PAL，PR1，PR5，GLU were up-regulated within 12 h to 24 h of H. uvarum + B. cinerea treatment，which are the marker genes of SA signaling pathway，and the up-regulation was higher than that of H. uvarum or B. cinerea treatment alone. But the PDF1 and JAR1 genes of JA signaling pathway were not accumulated in each treatment. H. uvarum challenged with B. cinerea treatment can increase the SOD，APX，PAL and CAT enzyme activity in a short time，which are involved in plant defense. The H. uvarum treatment also can delay the deterioration of fruit and maintain high quality during the cold storage period.

Key words: strawberry, gray mold, postharvest, Hanseniaspora uvarum, induced resistance, salicylic acid signaling pathway