Abstract: To accelerate the mining of potato germplasm with late blight resistance，the effectoromics strategy was used in this study. Sixty eight Phytophthora infestans RXLR effector genes that up-regulated early during infection stage were selected for recognition assay. These effector genes were cloned into the plant expression vector pGR106 and transiently expressed in leaves of 55 potato genotypes using toothpick inoculation with Agrobacterium cultures. Ten RXLR effector genes，including Pi23008（an AVR2 family number），RD39（AVRblb2），RD2（a cell death inducer），and other unknown function effector genes （Pex147-2，PexRD8，PexRD49，PITG_10232，PITG_11484，PITG_07555 and PITG_22724），could induce the hypersensitive response（HR）on leaves of a total of 10 potato genotypes，suggesting that these potato materials potentially carry R genes corresponding to particular effectors. In addition，the potato material IVP196-2 that could recognize 6 RXLR effectors，showed a higher level of late-blight resistance when compared to HJT349-3，which could only recognize 3 effectors.

Key words: potato, Phytophthora infestans, effector, hypersensitive response, avirulence gene