Abstract: The healing process of potato tubers consists of the formation of‘closing layers’and ‘wound periderm’，the former refers to the suberization of parenchyma cells neighboring wound site，and the later refers to the suberized phellem cells beneath the closing layers. As the primary barrier of suberization，‘closing layers’inhibit the pathogen infection，however，a persistent protective structure against pathogens on wounded tubers mainly depends on‘wound periderm’. Various metabolic pathways are involved in the healing of tubers，and among them，reactive oxygen species，phenylpropanoid and fatty acid metabolism play essential roles in the formation of healing tissues. The potato cultivars and tuber maturity are main factors affecting wound healing. Additionally，temperature，relative humidity，light radiation，O2 and CO2 concentration，wounding severity，and chemicals affect the wound healing of tubers.

Key words: potato, tuber, wound healing, mechanism, influential factor