Advances in the Functional Studies of MYC2 Transcription Factor in Plants

doi:10.16420/j.issn.0513-353x.2022-0102

Acta Horticulturae Sinica ›› 2023, Vol. 50 ›› Issue (4): 896-908.doi: 10.16420/j.issn.0513-353x.2022-0102

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Advances in the Functional Studies of MYC2 Transcription Factor in Plants

ZHENG Jiarui, YANG Xiaoyan, YE Jiabao, LIAO Yongling(), XU Feng()

College of Horticulture and Gardening，Yangtze University，Jingzhou，Hubei 434025，China

Received:2022-09-06 Revised:2022-12-02 Online:2023-04-25 Published:2023-04-27
Contact: *（E-mail：liaoyongling@yangtzeu.edu.cn；xufeng198@126.com）

Abstract

Abstract:

MYC2（Myelocytomatosis proteins 2），a transcription factor in the bHLH family，is the main regulator in JA signaling. MYC2 participates in life activities such as stress defense，growth and development，and secondary metabolism by regulating the transcription and expression of downstream target genes. As a secondary regulator of JA signaling，MYC3/4 can cooperate with MYC2. At present，the functional mechanism of MYC2 has been studied deeply and extensively. This paper summarizes the structural characteristics of MYC2 and its regulatory mechanisms in plant hormone signaling，stress defense，growth and development，and secondary metabolism，providing a theoretical basis for further investigation molecular functions of MYC2.

Key words: MYC2 transcription factor, signal transduction, adverse stress, growth and development, secondary metabolism

CLC Number:

ZHENG Jiarui, YANG Xiaoyan, YE Jiabao, LIAO Yongling, XU Feng. Advances in the Functional Studies of MYC2 Transcription Factor in Plants[J]. Acta Horticulturae Sinica, 2023, 50(4): 896-908.

Figures/Tables 5

Fig. 1 Phylogenetic relationships of MYC2 among different species

Fig. 2 The network of MYC2 involved in plant hormone synthesis and signal transduction PRP39a/40a：PRE-mRNA-Processing Protein 39a/40a；MED25：Mediator Complex Subunit 25；CUL3BPM： Cullin 3，BPM，BTB/POZ-MATH；UBP12/13：Ubiquttin-specific protease 12/13；EDS5：Enhanced disease susceptibility 5；PAD4：Phytoalexin deficient 4；DELLA：DELLA protein；JAM：JA-ASSOCIATED MYC2-LIKE transcription factor；JAZ：Jasmonate-ZIM domain protein；MTB：MYC2-TARGETED BHLH transcription factor.

Fig. 3 The network of MYC2 involved in biotic and abiotic stress in plants At：Arabidopsis thaliana；Ma：Musa acuminata；Ptr：Poncirus trifoliata；Sl：Solanum lycopersicum；Ca：Capsicum annuum；Os：Oryza sativa. COR：Coronatine；PDF：Plant defense factor；PI：Proteinase inhibitor；NAC：NAC transcription factor；VSP：Vegetative storage protein；ICE：Inducer of CBF（C-repeat-binging factors）expression；BADH：Betaine aldehyde dehydrogenase；CAT：Catalase；NSs：Non-structural protein of tomato spotted wilt orthotospovirus（TSWV）；TPS：Terpene synthase；TD：Threonine deaminase；P1BS：Program in biomedical sciences；SPX：SPX protein.

Fig. 4 MYC2 participates in the regulation network of plant secondary metabolism At：Arabidopsis thaliana；Na：Nicotiana attenuata；As：Aquilaria sinensis；Md：Malus × domestica；Tc：Taxus chinensis；Tw：Tripterygium wilfordii；Nt：Nicotiana tabacum；Sm：Salvia miltiorrhiza；Cr：Catharanthus roseus；Fh：Freesia hybrida.ASS：Sesquiterpene synthase；PMT：Putrescine N-methyltransferase；RMT1：Repressor of MYC2 targets 1；BIS：bHLH iridoid synthesis；MIA：Monoterpene indole alkaloid.

Fig. 5 MYC2 participates in the regulation network of plant growth and development Md：Malus × domestica；At：Arabidopsis thaliana；Le：Lycopersicon esculentum.MPK：Mitogen-activated protein kinase；HY5：Hypocotyl 5；USR：U-box senescence related；SAG：Senescence-associated gene；SPCH：SPEECHLESS.

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Advances in the Functional Studies of MYC2 Transcription Factor in Plants

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