Abstract: Root-knot nematodes (Meloidogyne spp. ) are obligate, sedentary endoparasites nematodes.The interaction between root-knot nematodes and plants is complex, which involved a series ofmolecular signs identification, regulation and genes expression. In suscep tible host, following infection of the host root, Root-knot nematode modifies one or more plant cells, which causes their re-differentiation into a specialized feeding site that supports development of a sedentary, feeding and rep roductively competent female. Root knot nematodes form giant cells by inducing plant cellmitosis without concomitant cytokinesis. In resistance host, Root-knot nematode triggers plant resistance responses to defense the nematodes invading, migrating or interfering with forms of feeding site. Some resistant-nematode genes have been cloned. It is generally accep ted that the secretions of Root-knot nematodes are key in the molecular interaction between Root-knot nematodes and plants. The interaction results in the host resistance or susceptibility. The research on the early molecular express in resistant host induced by nematode, the special transcrip t p romoters in the root and the virulent/avirulent genes et al will become a hot field.

Key words: Root-knot nematodes, Secretion, Resistance gene, Molecular interaction, Review