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园艺学报 ›› 2018, Vol. 45 ›› Issue (1): 177-192.doi: 10.16420/j.issn.0513-353x.2017-0306

• 综述 • 上一篇    下一篇

植物黄酮醇生物合成及其调控研究进展

曹运琳,邢梦云,徐昌杰,李 鲜*   

  1. 浙江大学园艺系,浙江省园艺植物整合生物学研究与应用重点实验室,杭州 310058
  • 出版日期:2018-01-25 发布日期:2018-01-25

Biosynthesis of Flavonol and Its Regulation in Plants

CAO Yunlin,XING Mengyun,XU Changjie,and LI Xian*   

  1. Department of Horticulture,Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology,Zhejiang University,Hangzhou 310058,China
  • Online:2018-01-25 Published:2018-01-25

摘要: 植物黄酮醇具有广泛生物活性,其生物合成及其调控研究日益增多,逐渐成为热点。对黄酮醇生物合成关键酶(FLS、F3H、F3′H、F3′5′H、UGT)和调控因子(如MYB等转录因子)相关的生化与分子生物学研究进展进行总结,重点对相关结构基因和转录因子对黄酮醇积累发挥关键作用的试验证据进行归纳,探索调控黄酮醇物质积累的有效途径及靶标分子,以期为利用基因工程定向积累具有重要生物学功能的黄酮醇物质提供参考。

关键词: 黄酮醇, 生物合成, 代谢调控, 分子机制, 基因工程

Abstract: Flavonol has a wide range of biological activities and studies on biosynthesis and regulation of flavonol in plant attract more attention. Here,research progress in key enzymes(FLS,F3H,F3′H,F3′5′H,UGT)and regulatory factors(e.g. MYB transcription factors)in flavonol biosynthetic pathway were summarized from biochemical and molecular biological points of view. Important evidence illustrating key structure genes or regulatory factors playing critical roles in flavonol biosynthesis are emphasized,which may result in efficient regulation of target molecules and accumulation of flavonol compounds with important biological functions via genetic engineering.

Key words: flavonol, biosynthesis, regulation, molecular mechanism, genetic engineering