Abstract: A major bottleneck of crop breeding is the narrow genetic base of cultivated species. It is a must to introgress new beneficial alleles from wild germp lasm. Due to crossing barrier and linkage drag, conventional breeding isnpt effective in use of these beneficial alleles. The rap id development of genomics enables
the isolation of a number of plant genes in an easyway. Cisgenesis is a genetic modification app roach to quickly transfer beneficial alleles from crossable species into elite cultivars. This app roach will not only speed up breeding process but also avoid linkage drag. As the origins of target genes by cisgenesis and conventional breeding are the same, cultivars released by these two app roaches are same in safety. If regulators could treat cisgenic plants the same as conventionally bred p lants, cisgenesis will become an effective tool of crop improvement in use of wild germplasm.

Key words: Crop breeding, Cisgenesis, Safety evaluation